Towards direct neuronal current imaging with MR: potentials and limitations

Extracting quantitative information on neuronal signals by non-invasive imaging is an outstanding challenge for understanding brain function and pathology. Still, currently established fMRI methods such as BOLD or diffusion, measure neuronal activation indirectly. Stimulus-induced rotary saturation (SIRS) has been recently proposed as a promising tool to detect neuronal fields and reconstruct functional connectivity using MRI. The principle of the technique is based on a double resonance effect produced when the Larmor frequency induced by a Spin Lock (SL) preparation pulse matches the frequency of an oscillating neuronal field.

In this talk, I will present the concepts of magnetic resonance-based neuronal current imaging and the current state of the art in developing this technique. In addition, I will show the potential and limitations of its application in clinical practice.

The lecture will be held as a zoom meeting, please connect using:

https://unibe-ch.zoom.us/j/61954796127?pwd=b25nSWVIVi9PWlV4Vlp3NXpMdjRQdz09

For further info please contact: bernd.jung@insel.ch